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Combination Therapy With Rapamycin and Low Dose Imatinib in Pulmonary Hypertension

Rationale: Enhanced proliferation and distal migration of human pulmonary arterial smooth muscle cells (hPASMCs) both contribute to the progressive increases in pulmonary vascular remodeling and resistance in pulmonary arterial hypertension (PAH). Our previous studies revealed that Rictor deletion,...

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Detalles Bibliográficos
Autores principales: Shi, Yinan, Gu, Chenxin, Zhao, Tongtong, Jia, Yangfan, Bao, Changlei, Luo, Ang, Guo, Qiang, Han, Ying, Wang, Jian, Black, Stephen M., Desai, Ankit A., Tang, Haiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632256/
https://www.ncbi.nlm.nih.gov/pubmed/34858182
http://dx.doi.org/10.3389/fphar.2021.758763