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Improving cancer immunotherapy by targeting IL-1
Interleukin-1 (IL-1) is an inflammatory cytokine associated with tumor invasiveness and metastasis. We recently found that baseline IL-1 in melanomas promoted resistance to immunotherapy by creating an immunosuppressive tumor microenvironment and that IL-1 produced in response to CD40 agonist also i...
Autores principales: | Xiao, Zhilan, Singh, Shubhra, Singh, Manisha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632280/ https://www.ncbi.nlm.nih.gov/pubmed/34858734 http://dx.doi.org/10.1080/2162402X.2021.2008111 |
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