Tumor cell-derived IL-10 promotes cell-autonomous growth and immune escape in diffuse large B-cell lymphoma

Diffuse large B-cell lymphoma (DLBCL) is an aggressive malignancy arising from germinal center or post-germinal center B-cells that retain many of the properties of normal B-cells. Here we show that a subset of DLBCL express the cytokine IL-10 and its receptor. The genetic ablation of IL-10 receptor...

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Detalles Bibliográficos
Autores principales: Stirm, Kristin, Leary, Peter, Bertram, Katrin, Núñez, Nicolás Gonzalo, Wüst, Daria, Boudesco, Christophe, Verhoeyen, Els, Zenz, Thorsten, Becher, Burkhard, Menter, Thomas, Tzankov, Alexandar, Müller, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632300/
https://www.ncbi.nlm.nih.gov/pubmed/34858727
http://dx.doi.org/10.1080/2162402X.2021.2003533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632300/
https://www.ncbi.nlm.nih.gov/pubmed/34858727
http://dx.doi.org/10.1080/2162402X.2021.2003533

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