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Unifying heterogeneous expression data to predict targets for CAR-T cell therapy
Chimeric antigen receptor (CAR) T-cell therapy combines antigen-specific properties of monoclonal antibodies with the lytic capacity of T cells. An effective and safe CAR-T cell therapy strategy relies on identifying an antigen that has high expression and is tumor specific. This strategy has been s...
Autores principales: | Schreiner, Patrick, Velasquez, Mireya Paulina, Gottschalk, Stephen, Zhang, Jinghui, Fan, Yiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632331/ https://www.ncbi.nlm.nih.gov/pubmed/34858726 http://dx.doi.org/10.1080/2162402X.2021.2000109 |
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