Tissue Type Differences in ABCB1 Expression and Paclitaxel Tissue Pharmacokinetics in Patients With Esophageal Cancer

Background: Data from previous work suggests that there is no correlation between systemic (plasma) paclitaxel exposure and efficacy in patients treated for esophageal cancer. In this trial, we investigated ATP-binding cassette efflux transporter expression and intratumoral pharmacokinetics of pacli...

Descripción completa

Detalles Bibliográficos
Autores principales: van Eerden, Ruben A. G., van Doorn, Leni, de Man, Femke M., Heersche, Niels, Doukas, Michail, van den Bosch, Thierry P. P., Oomen-de Hoop, Esther, de Bruijn, Peter, Bins, Sander, Ibrahim, Eman, Nikkessen, Suzan, Friberg, Lena E., Koolen, Stijn L. W., Spaander, Manon C. W., Mathijssen, Ron H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632367/
https://www.ncbi.nlm.nih.gov/pubmed/34858183
http://dx.doi.org/10.3389/fphar.2021.759146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632367/
https://www.ncbi.nlm.nih.gov/pubmed/34858183
http://dx.doi.org/10.3389/fphar.2021.759146

Ejemplares similares