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Treatment of Severe Acute Pancreatitis and Related Lung Injury by Targeting Gasdermin D-Mediated Pyroptosis

The functional relevance and effects of the pyroptosis executioner gasdermin D (GSDMD) on severe acute pancreatitis (SAP)-associated lung injury are unclear. We established caerulein-induced mouse models of SAP-associated lung injury, which showed that GSDMD-mediated pyroptosis was activated in both...

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Detalles Bibliográficos
Autores principales:	Wu, Jinxiang, Zhang, Jintao, Zhao, Jiping, Chen, Shihong, Zhou, Tao, Xu, Jianwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632453/ https://www.ncbi.nlm.nih.gov/pubmed/34858995 http://dx.doi.org/10.3389/fcell.2021.780142

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