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Analysis of Influencing Factors of Repair Effect after Peripheral Nerve Injury

In order to improve the repair effect after peripheral nerve injury, this paper analyzes the related influencing factors. The regeneration of peripheral nerve includes two continuous and overlapping processes: the acute wound healing period and the axon seeking target tissue period. The complete and...

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Detalles Bibliográficos
Autores principales: Mao, Renqun, Wei, Zean, Li, Wenqing, Zhu, Xiaodi, Du, Dalian, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632468/
https://www.ncbi.nlm.nih.gov/pubmed/34858520
http://dx.doi.org/10.1155/2021/8294267
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author Mao, Renqun
Wei, Zean
Li, Wenqing
Zhu, Xiaodi
Du, Dalian
Xu, Wei
author_facet Mao, Renqun
Wei, Zean
Li, Wenqing
Zhu, Xiaodi
Du, Dalian
Xu, Wei
author_sort Mao, Renqun
collection PubMed
description In order to improve the repair effect after peripheral nerve injury, this paper analyzes the related influencing factors. The regeneration of peripheral nerve includes two continuous and overlapping processes: the acute wound healing period and the axon seeking target tissue period. The complete and effective process of peripheral nerve regeneration includes the sprouting, growth and extension of regenerated axons, and the reconstruction of synaptic connections (neuromuscular junctions) with target organs to realize the reinnervation of nerves and restore function. This process includes three indicators of success in regeneration: structural reconstruction, metabolic regeneration, and functional recovery. In order to improve the repair effect of peripheral nerve injury, relevant influencing factors can be analyzed, and effective improvement of these influencing factors can improve the recovery effect of peripheral nerve injury. Finally, this paper analyzes multiple factors to provide theoretical references for follow-up clinical diagnosis and treatment.
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spelling pubmed-86324682021-12-01 Analysis of Influencing Factors of Repair Effect after Peripheral Nerve Injury Mao, Renqun Wei, Zean Li, Wenqing Zhu, Xiaodi Du, Dalian Xu, Wei Comput Math Methods Med Research Article In order to improve the repair effect after peripheral nerve injury, this paper analyzes the related influencing factors. The regeneration of peripheral nerve includes two continuous and overlapping processes: the acute wound healing period and the axon seeking target tissue period. The complete and effective process of peripheral nerve regeneration includes the sprouting, growth and extension of regenerated axons, and the reconstruction of synaptic connections (neuromuscular junctions) with target organs to realize the reinnervation of nerves and restore function. This process includes three indicators of success in regeneration: structural reconstruction, metabolic regeneration, and functional recovery. In order to improve the repair effect of peripheral nerve injury, relevant influencing factors can be analyzed, and effective improvement of these influencing factors can improve the recovery effect of peripheral nerve injury. Finally, this paper analyzes multiple factors to provide theoretical references for follow-up clinical diagnosis and treatment. Hindawi 2021-11-23 /pmc/articles/PMC8632468/ /pubmed/34858520 http://dx.doi.org/10.1155/2021/8294267 Text en Copyright © 2021 Renqun Mao et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Mao, Renqun
Wei, Zean
Li, Wenqing
Zhu, Xiaodi
Du, Dalian
Xu, Wei
Analysis of Influencing Factors of Repair Effect after Peripheral Nerve Injury
title Analysis of Influencing Factors of Repair Effect after Peripheral Nerve Injury
title_full Analysis of Influencing Factors of Repair Effect after Peripheral Nerve Injury
title_fullStr Analysis of Influencing Factors of Repair Effect after Peripheral Nerve Injury
title_full_unstemmed Analysis of Influencing Factors of Repair Effect after Peripheral Nerve Injury
title_short Analysis of Influencing Factors of Repair Effect after Peripheral Nerve Injury
title_sort analysis of influencing factors of repair effect after peripheral nerve injury
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632468/
https://www.ncbi.nlm.nih.gov/pubmed/34858520
http://dx.doi.org/10.1155/2021/8294267
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