Immunogenicity and Protective Potential of Mucosal Vaccine Formulations Based on Conserved Epitopes of Influenza A Viruses Fused to an Innovative Ring Nanoplatform in Mice and Chickens

Current inactivated vaccines against influenza A viruses (IAV) mainly induce immune responses against highly variable epitopes across strains and are mostly delivered parenterally, limiting the development of an effective mucosal immunity. In this study, we evaluated the potential of intranasal form...

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Detalles Bibliográficos
Autores principales: Calzas, Cynthia, Mao, Molida, Turpaud, Mathilde, Viboud, Quentin, Mettier, Joelle, Figueroa, Thomas, Bessière, Pierre, Mangin, Antoine, Sedano, Laura, Hervé, Pierre-Louis, Volmer, Romain, Ducatez, Mariette F., Bourgault, Steve, Archambault, Denis, Le Goffic, Ronan, Chevalier, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632632/
https://www.ncbi.nlm.nih.gov/pubmed/34868036
http://dx.doi.org/10.3389/fimmu.2021.772550

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