Loss of Profilin3 Impairs Spermiogenesis by Affecting Acrosome Biogenesis, Autophagy, Manchette Development and Mitochondrial Organization

Profilins (PFNs) are key regulatory proteins for the actin polymerization in cells and are encoded in mouse and humans by four Pfn genes. PFNs are involved in cell mobility, cell growth, neurogenesis, and metastasis of tumor cells. The testes-specific PFN3 is localized in the acroplaxome–manchette c...

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Detalles Bibliográficos
Autores principales: Umer, Naila, Arévalo, Lena, Phadke, Sharang, Lohanadan, Keerthika, Kirfel, Gregor, Sons, Dominik, Sofia, Denise, Witke, Walter, Schorle, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632698/
https://www.ncbi.nlm.nih.gov/pubmed/34869336
http://dx.doi.org/10.3389/fcell.2021.749559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632698/
https://www.ncbi.nlm.nih.gov/pubmed/34869336
http://dx.doi.org/10.3389/fcell.2021.749559

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