Advantages of Tailored Isotretinoin Treatment in Moderate to Severe Acne: Real-Life Data

This retrospective single-center study analyzes the efficacy and safety of isotretinoin for the treatment of moderate to severe acne in real-life clinical practice, particularly with regard to acne severity, isotretinoin cumulative dosage, and patients’ gender. The results suggest the opportunity of...

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Autores principales: Skroza, Nevena, Tolino, Ersilia, Balduzzi, Veronica, Bernardini, Nicoletta, Mambrin, Alessandra, Marchesiello, Anna, Marraffa, Federica, Rossi, Giovanni, Volpe, Salvatore, Proietti, Ilaria, Potenza, Concetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632712/
https://www.ncbi.nlm.nih.gov/pubmed/34867340
http://dx.doi.org/10.3389/fphar.2021.733526
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author Skroza, Nevena
Tolino, Ersilia
Balduzzi, Veronica
Bernardini, Nicoletta
Mambrin, Alessandra
Marchesiello, Anna
Marraffa, Federica
Rossi, Giovanni
Volpe, Salvatore
Proietti, Ilaria
Potenza, Concetta
author_facet Skroza, Nevena
Tolino, Ersilia
Balduzzi, Veronica
Bernardini, Nicoletta
Mambrin, Alessandra
Marchesiello, Anna
Marraffa, Federica
Rossi, Giovanni
Volpe, Salvatore
Proietti, Ilaria
Potenza, Concetta
author_sort Skroza, Nevena
collection PubMed
description This retrospective single-center study analyzes the efficacy and safety of isotretinoin for the treatment of moderate to severe acne in real-life clinical practice, particularly with regard to acne severity, isotretinoin cumulative dosage, and patients’ gender. The results suggest the opportunity of an early isotretinoin systemic treatment in patients affected by moderate acne and emphasize the importance of an appropriate dose adjustment in order to minimize adverse events.
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spelling pubmed-86327122021-12-02 Advantages of Tailored Isotretinoin Treatment in Moderate to Severe Acne: Real-Life Data Skroza, Nevena Tolino, Ersilia Balduzzi, Veronica Bernardini, Nicoletta Mambrin, Alessandra Marchesiello, Anna Marraffa, Federica Rossi, Giovanni Volpe, Salvatore Proietti, Ilaria Potenza, Concetta Front Pharmacol Pharmacology This retrospective single-center study analyzes the efficacy and safety of isotretinoin for the treatment of moderate to severe acne in real-life clinical practice, particularly with regard to acne severity, isotretinoin cumulative dosage, and patients’ gender. The results suggest the opportunity of an early isotretinoin systemic treatment in patients affected by moderate acne and emphasize the importance of an appropriate dose adjustment in order to minimize adverse events. Frontiers Media S.A. 2021-11-12 /pmc/articles/PMC8632712/ /pubmed/34867340 http://dx.doi.org/10.3389/fphar.2021.733526 Text en Copyright © 2021 Skroza, Tolino, Balduzzi, Bernardini, Mambrin, Marchesiello, Marraffa, Rossi, Volpe, Proietti and Potenza. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Skroza, Nevena
Tolino, Ersilia
Balduzzi, Veronica
Bernardini, Nicoletta
Mambrin, Alessandra
Marchesiello, Anna
Marraffa, Federica
Rossi, Giovanni
Volpe, Salvatore
Proietti, Ilaria
Potenza, Concetta
Advantages of Tailored Isotretinoin Treatment in Moderate to Severe Acne: Real-Life Data
title Advantages of Tailored Isotretinoin Treatment in Moderate to Severe Acne: Real-Life Data
title_full Advantages of Tailored Isotretinoin Treatment in Moderate to Severe Acne: Real-Life Data
title_fullStr Advantages of Tailored Isotretinoin Treatment in Moderate to Severe Acne: Real-Life Data
title_full_unstemmed Advantages of Tailored Isotretinoin Treatment in Moderate to Severe Acne: Real-Life Data
title_short Advantages of Tailored Isotretinoin Treatment in Moderate to Severe Acne: Real-Life Data
title_sort advantages of tailored isotretinoin treatment in moderate to severe acne: real-life data
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632712/
https://www.ncbi.nlm.nih.gov/pubmed/34867340
http://dx.doi.org/10.3389/fphar.2021.733526
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