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Compression of amorphous solid dispersions prepared by hot-melt extrusion, spray drying and vacuum drum drying

The present study explored vacuum drum drying (VDD) as an alternative technology for amorphous solid dispersions (ASDs) manufacture compared to hot-melt extrusion (HME) and spray drying (SD) focusing on downstream processability (powder properties, compression behavior and tablet performance). Riton...

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Detalles Bibliográficos
Autores principales: Schönfeld, Barbara V., Westedt, Ulrich, Wagner, Karl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632852/
https://www.ncbi.nlm.nih.gov/pubmed/34877525
http://dx.doi.org/10.1016/j.ijpx.2021.100102