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Compression of amorphous solid dispersions prepared by hot-melt extrusion, spray drying and vacuum drum drying
The present study explored vacuum drum drying (VDD) as an alternative technology for amorphous solid dispersions (ASDs) manufacture compared to hot-melt extrusion (HME) and spray drying (SD) focusing on downstream processability (powder properties, compression behavior and tablet performance). Riton...
Autores principales: | Schönfeld, Barbara V., Westedt, Ulrich, Wagner, Karl G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632852/ https://www.ncbi.nlm.nih.gov/pubmed/34877525 http://dx.doi.org/10.1016/j.ijpx.2021.100102 |
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