Cargando…
Fis1 phosphorylation by Met promotes mitochondrial fission and hepatocellular carcinoma metastasis
Met tyrosine kinase, a receptor for a hepatocyte growth factor (HGF), plays a critical role in tumor growth, metastasis, and drug resistance. Mitochondria are highly dynamic and undergo fission and fusion to maintain a functional mitochondrial network. Dysregulated mitochondrial dynamics are respons...
Autores principales: | Yu, Yan, Peng, Xiao-Dan, Qian, Xiao-Jun, Zhang, Kai-Ming, Huang, Xiang, Chen, Yu-Hong, Li, Yun-Tian, Feng, Gong-Kan, Zhang, Hai-Liang, Xu, Xue-Lian, Li, Shun, Li, Xuan, Mai, Jia, Li, Zhi-Ling, Huang, Yun, Yang, Dong, Zhou, Li-Huan, Zhong, Zhuo-Yan, Li, Jun-Dong, Deng, Rong, Zhu, Xiao-Feng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632923/ https://www.ncbi.nlm.nih.gov/pubmed/34848680 http://dx.doi.org/10.1038/s41392-021-00790-2 |
Ejemplares similares
-
Polo-Like Kinase 1 phosphorylates and stabilizes KLF4 to promote tumorigenesis in nasopharyngeal carcinoma
por: Mai, Jia, et al.
Publicado: (2019) -
MoDnm1 Dynamin Mediating Peroxisomal and Mitochondrial Fission in Complex with MoFis1 and MoMdv1 Is Important for Development of Functional Appressorium in Magnaporthe oryzae
por: Zhong, Kaili, et al.
Publicado: (2016) -
Autophagy deficiency promotes triple-negative breast cancer resistance to T cell-mediated cytotoxicity by blocking tenascin-C degradation
por: Li, Zhi-Ling, et al.
Publicado: (2020) -
The mitochondrial fission factor FIS1 promotes stemness of human lung cancer stem cells via mitophagy
por: Liu, Doudou, et al.
Publicado: (2021) -
PTEN-induced kinase 1-induced dynamin-related protein 1 Ser637 phosphorylation reduces mitochondrial fission and protects against intestinal ischemia reperfusion injury
por: Qasim, Wasim, et al.
Publicado: (2020)