Coordination of retrotransposons and type I interferon with distinct interferon pathways in dermatomyositis, systemic lupus erythematosus and autoimmune blistering disease

Type I interferon (IFN) plays a crucial role in innate and adaptive immunity, and aberrant IFN responses are involved in systemic autoimmune diseases, such as systemic lupus erythematosus (SLE) and dermatomyositis (DM). Type I IFNs can be induced by transcribed retrotransposons. The regulation of re...

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Detalles Bibliográficos
Autores principales: Kuriyama, Yuko, Shimizu, Akira, Kanai, Saki, Oikawa, Daisuke, Motegi, Sei-ichiro, Tokunaga, Fuminori, Ishikawa, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632942/
https://www.ncbi.nlm.nih.gov/pubmed/34848794
http://dx.doi.org/10.1038/s41598-021-02522-6

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