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Recurrent integration of human papillomavirus genomes at transcriptional regulatory hubs

Oncogenic human papillomavirus (HPV) genomes are often integrated into host chromosomes in HPV-associated cancers. HPV genomes are integrated either as a single copy or as tandem repeats of viral DNA interspersed with, or without, host DNA. Integration occurs frequently in common fragile sites susce...

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Detalles Bibliográficos
Autores principales: Warburton, Alix, Markowitz, Tovah E., Katz, Joshua P., Pipas, James M., McBride, Alison A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632991/
https://www.ncbi.nlm.nih.gov/pubmed/34848725
http://dx.doi.org/10.1038/s41525-021-00264-y