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Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension

Despite the association of cholesterol with debilitating pressure-related diseases such as glaucoma, heart disease, and diabetes, its role in mechanotransduction is not well understood. We investigated the relationship between mechanical strain, free membrane cholesterol, actin cytoskeleton, and the...

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Detalles Bibliográficos
Autores principales:	Lakk, Monika, Hoffmann, Grace F., Gorusupudi, Aruna, Enyong, Eric, Lin, Amy, Bernstein, Paul S., Toft-Bertelsen, Trine, MacAulay, Nanna, Elliott, Michael H., Križaj, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633027/ https://www.ncbi.nlm.nih.gov/pubmed/34710431 http://dx.doi.org/10.1016/j.jlr.2021.100145

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