Mbnl1 and Mbnl2 regulate brain structural integrity in mice

Myotonic Dystrophy Type I (DM1) patients demonstrate widespread and variable brain structural alterations whose etiology is unclear. We demonstrate that inactivation of the Muscleblind-like proteins, Mbnl1 and Mbnl2, initiates brain structural defects. 2D FSE T2w MRIs on 4-month-old Mbnl1(+/−)/Mbnl2...

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Detalles Bibliográficos
Autores principales: Sta Maria, Naomi S., Zhou, Chenyu, Lee, Se Jung, Valiulahi, Parvin, Li, Xiandu, Choi, Jongkyu, Liu, Xiaodan, Jacobs, Russell, Comai, Lucio, Reddy, Sita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633067/
https://www.ncbi.nlm.nih.gov/pubmed/34848815
http://dx.doi.org/10.1038/s42003-021-02845-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633067/
https://www.ncbi.nlm.nih.gov/pubmed/34848815
http://dx.doi.org/10.1038/s42003-021-02845-0

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