Cyclosporine A Induces Cardiac Developmental Toxicity in Zebrafish by Up-Regulation of Wnt Signaling and Oxidative Stress

Due to the widely application of Cyclosporine A (CsA) as an immunosuppressant in clinic, it is necessary to study its potential toxicity. Therefore, we used zebrafish as a model animal to evaluate the toxicity of CsA on embryonic development. Exposure of zebrafish embryos to CsA at concentrations of...

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Detalles Bibliográficos
Autores principales: Wan, Mengqi, Huang, Ling, Liu, Jieping, Liu, Fasheng, Chen, Guilan, Ni, Huiwen, Xiong, Guanghua, Liao, Xinjun, Lu, Huiqiang, Xiao, Juhua, Tao, Qiang, Cao, Zigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633111/
https://www.ncbi.nlm.nih.gov/pubmed/34867350
http://dx.doi.org/10.3389/fphar.2021.747991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633111/
https://www.ncbi.nlm.nih.gov/pubmed/34867350
http://dx.doi.org/10.3389/fphar.2021.747991

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