Co-expression of Myoepithelial and Melanocytic Features in Carcinoma Ex Pleomorphic Adenoma

The presence of melanin pigment and melanocytic markers expression have been rarely reported in salivary gland tumors. Herein, two cases of carcinoma arising in pleomorphic adenoma of the parotid gland and showing diffuse expression of myoepithelial and melanocytic markers are described. The clinica...

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Autores principales: Ricci, Costantino, Chiarucci, Federico, Ambrosi, Francesca, Balbi, Tiziana, Corti, Barbara, Piccin, Ottavio, Pasquini, Ernesto, Foschini, Maria Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633150/
https://www.ncbi.nlm.nih.gov/pubmed/33591488
http://dx.doi.org/10.1007/s12105-021-01299-4
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author Ricci, Costantino
Chiarucci, Federico
Ambrosi, Francesca
Balbi, Tiziana
Corti, Barbara
Piccin, Ottavio
Pasquini, Ernesto
Foschini, Maria Pia
author_facet Ricci, Costantino
Chiarucci, Federico
Ambrosi, Francesca
Balbi, Tiziana
Corti, Barbara
Piccin, Ottavio
Pasquini, Ernesto
Foschini, Maria Pia
author_sort Ricci, Costantino
collection PubMed
description The presence of melanin pigment and melanocytic markers expression have been rarely reported in salivary gland tumors. Herein, two cases of carcinoma arising in pleomorphic adenoma of the parotid gland and showing diffuse expression of myoepithelial and melanocytic markers are described. The clinical-pathological clues useful in the differential diagnosis with melanoma are discussed. In addition, a review of the pertinent literature is also proposed, discussing the pathologic mechanisms potentially involved in this phenomenon. SUPPLEMENTARY INFORMATION: The online version of this article (10.1007/s12105-021-01299-4) contains supplementary material, which is available to authorized users.
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spelling pubmed-86331502021-12-15 Co-expression of Myoepithelial and Melanocytic Features in Carcinoma Ex Pleomorphic Adenoma Ricci, Costantino Chiarucci, Federico Ambrosi, Francesca Balbi, Tiziana Corti, Barbara Piccin, Ottavio Pasquini, Ernesto Foschini, Maria Pia Head Neck Pathol Case Reports The presence of melanin pigment and melanocytic markers expression have been rarely reported in salivary gland tumors. Herein, two cases of carcinoma arising in pleomorphic adenoma of the parotid gland and showing diffuse expression of myoepithelial and melanocytic markers are described. The clinical-pathological clues useful in the differential diagnosis with melanoma are discussed. In addition, a review of the pertinent literature is also proposed, discussing the pathologic mechanisms potentially involved in this phenomenon. SUPPLEMENTARY INFORMATION: The online version of this article (10.1007/s12105-021-01299-4) contains supplementary material, which is available to authorized users. Springer US 2021-02-16 /pmc/articles/PMC8633150/ /pubmed/33591488 http://dx.doi.org/10.1007/s12105-021-01299-4 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Case Reports
Ricci, Costantino
Chiarucci, Federico
Ambrosi, Francesca
Balbi, Tiziana
Corti, Barbara
Piccin, Ottavio
Pasquini, Ernesto
Foschini, Maria Pia
Co-expression of Myoepithelial and Melanocytic Features in Carcinoma Ex Pleomorphic Adenoma
title Co-expression of Myoepithelial and Melanocytic Features in Carcinoma Ex Pleomorphic Adenoma
title_full Co-expression of Myoepithelial and Melanocytic Features in Carcinoma Ex Pleomorphic Adenoma
title_fullStr Co-expression of Myoepithelial and Melanocytic Features in Carcinoma Ex Pleomorphic Adenoma
title_full_unstemmed Co-expression of Myoepithelial and Melanocytic Features in Carcinoma Ex Pleomorphic Adenoma
title_short Co-expression of Myoepithelial and Melanocytic Features in Carcinoma Ex Pleomorphic Adenoma
title_sort co-expression of myoepithelial and melanocytic features in carcinoma ex pleomorphic adenoma
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633150/
https://www.ncbi.nlm.nih.gov/pubmed/33591488
http://dx.doi.org/10.1007/s12105-021-01299-4
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