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Homeoprotein SIX1 compromises antitumor immunity through TGF-β-mediated regulation of collagens

The tumor microenvironment (TME), including infiltrated immune cells, is known to play an important role in tumor growth; however, the mechanisms underlying tumor immunogenicity have not been fully elucidated. Here, we discovered an unexpected role for the transcription factor SIX1 in regulating the...

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Detalles Bibliográficos
Autores principales: Liu, Wancheng, Gao, Meiling, Li, Lili, Chen, Yu, Fan, Huimin, Cai, Qiaomei, Shi, Yueyue, Pan, Chaohu, Liu, Junxiao, Cheng, Lucy S., Yang, Heng, Cheng, Genhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633173/
https://www.ncbi.nlm.nih.gov/pubmed/34782761
http://dx.doi.org/10.1038/s41423-021-00800-x

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