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Deconvolution of Bulk Gene Expression Profiles with Single-Cell Transcriptomics to Develop a Cell Type Composition-Based Prognostic Model for Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is one of the malignant hematologic cancers with rapid progress and poor prognosis. Most AML prognostic stratifications focused on genetic abnormalities. However, none of them was established based on the cell type compositions (CTCs) of peripheral blood or bone marrow a...

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Detalles Bibliográficos
Autores principales:	Dai, Chengguqiu, Chen, Mengya, Wang, Chaolong, Hao, Xingjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633313/ https://www.ncbi.nlm.nih.gov/pubmed/34869351 http://dx.doi.org/10.3389/fcell.2021.762260

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