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A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilising immunity against SARS-CoV-2 infection

Global control of COVID-19 requires broadly accessible vaccines that are effective against SARS-CoV-2 variants. In this report, we exploit the immunostimulatory properties of bacille Calmette-Guérin (BCG), the existing tuberculosis vaccine, to deliver a vaccination regimen with potent SARS-CoV-2-spe...

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Detalles Bibliográficos
Autores principales: Counoupas, Claudio, Johansen, Matt D., Stella, Alberto O., Nguyen, Duc H., Ferguson, Angela L., Aggarwal, Anupriya, Bhattacharyya, Nayan D., Grey, Alice, Hutchings, Owen, Patel, Karishma, Siddiquee, Rezwan, Stewart, Erica L., Feng, Carl G., Hansbro, Nicole G., Palendira, Umaimainthan, Steain, Megan C., Saunders, Bernadette M., Low, Jason K. K., Mackay, Joel P., Kelleher, Anthony D., Britton, Warwick J., Turville, Stuart G., Hansbro, Philip M., Triccas, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633321/
https://www.ncbi.nlm.nih.gov/pubmed/34848711
http://dx.doi.org/10.1038/s41541-021-00406-4