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Therapeutic Targeting of Nonalcoholic Fatty Liver Disease by Downregulating SREBP-1C Expression via AMPK-KLF10 Axis

Krüppel-like factor 10 (KLF10) is a phospho-regulated transcriptional factor involved in many biological processes including lipogenesis; however, the transcriptional regulation on lipogenesis by KLF10 remains largely unclear. Lipogenesis is important in the development of nonalcoholic fatty liver d...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Chi, Chen, Rong-Jane, Peng, Szu-Yuan, Yu, Winston C. Y., Chang, Vincent Hung-Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633436/
https://www.ncbi.nlm.nih.gov/pubmed/34869587
http://dx.doi.org/10.3389/fmolb.2021.751938