Anti-inflammatory effects of N-cyclooctyl-5-methylthiazol-2-amine hydrobromide on lipopolysaccharide-induced inflammatory response through attenuation of NLRP3 activation in microglial cells

Microglial activation is closely associated with neuroinflammatory pathologies. The nucleotide-binding and oligomerization domain-like receptor containing a pyrin domain 3 (NLRP3) inflammasomes are highly organized intracellular sensors of neuronal alarm signaling. NLRP3 inflammasomes activate nucle...

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Detalles Bibliográficos
Autores principales: Kim, Eun-A, Hwang, Kyouk, Kim, Ji-Eun, Ahn, Jee-Yin, Choi, Soo Young, Yang, Seung-Ju, Cho, Sung-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633521/
https://www.ncbi.nlm.nih.gov/pubmed/34353430
http://dx.doi.org/10.5483/BMBRep.2021.54.11.082

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