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Urine-derived stem cells: applications in skin, bone and articular cartilage repair
As an emerging type of adult stem cell featuring non-invasive acquisition, urine-derived stem cells (USCs) have shown great potential for applications in tissue engineering and regenerative medicine. With a growing amount of research on the topic, the effectiveness of USCs in various disease models...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633594/ https://www.ncbi.nlm.nih.gov/pubmed/34859109 http://dx.doi.org/10.1093/burnst/tkab039 |
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author | Zhang, Wenqian Hu, Jungen Huang, Yizhou Wu, Chenyu Xie, Huiqi |
author_facet | Zhang, Wenqian Hu, Jungen Huang, Yizhou Wu, Chenyu Xie, Huiqi |
author_sort | Zhang, Wenqian |
collection | PubMed |
description | As an emerging type of adult stem cell featuring non-invasive acquisition, urine-derived stem cells (USCs) have shown great potential for applications in tissue engineering and regenerative medicine. With a growing amount of research on the topic, the effectiveness of USCs in various disease models has been shown and the underlying mechanisms have also been explored, though many aspects still remain unclear. In this review, we aim to provide an up-to-date overview of the biological characteristics of USCs and their applications in skin, bone and articular cartilage repair. In addition to the identification procedure of USCs, we also summarize current knowledge of the underlying repair mechanisms and application modes of USCs. Potential concerns and perspectives have also been summarized. |
format | Online Article Text |
id | pubmed-8633594 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-86335942021-12-01 Urine-derived stem cells: applications in skin, bone and articular cartilage repair Zhang, Wenqian Hu, Jungen Huang, Yizhou Wu, Chenyu Xie, Huiqi Burns Trauma Review As an emerging type of adult stem cell featuring non-invasive acquisition, urine-derived stem cells (USCs) have shown great potential for applications in tissue engineering and regenerative medicine. With a growing amount of research on the topic, the effectiveness of USCs in various disease models has been shown and the underlying mechanisms have also been explored, though many aspects still remain unclear. In this review, we aim to provide an up-to-date overview of the biological characteristics of USCs and their applications in skin, bone and articular cartilage repair. In addition to the identification procedure of USCs, we also summarize current knowledge of the underlying repair mechanisms and application modes of USCs. Potential concerns and perspectives have also been summarized. Oxford University Press 2021-11-26 /pmc/articles/PMC8633594/ /pubmed/34859109 http://dx.doi.org/10.1093/burnst/tkab039 Text en © The Author(s) 2021. Published by Oxford University Press. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Review Zhang, Wenqian Hu, Jungen Huang, Yizhou Wu, Chenyu Xie, Huiqi Urine-derived stem cells: applications in skin, bone and articular cartilage repair |
title | Urine-derived stem cells: applications in skin, bone and articular cartilage repair |
title_full | Urine-derived stem cells: applications in skin, bone and articular cartilage repair |
title_fullStr | Urine-derived stem cells: applications in skin, bone and articular cartilage repair |
title_full_unstemmed | Urine-derived stem cells: applications in skin, bone and articular cartilage repair |
title_short | Urine-derived stem cells: applications in skin, bone and articular cartilage repair |
title_sort | urine-derived stem cells: applications in skin, bone and articular cartilage repair |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633594/ https://www.ncbi.nlm.nih.gov/pubmed/34859109 http://dx.doi.org/10.1093/burnst/tkab039 |
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