Caspase-6 promotes activation of the caspase-11-NLRP3 inflammasome during gram-negative bacterial infections

The innate immune system acts as the first line of defense against infection. One key component of the innate immune response to gram-negative bacterial infections is inflammasome activation. The caspase-11 (CASP11)-nucleotide-binding oligomerization domain-like receptor pyrin domain-containing 3 (N...

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Detalles Bibliográficos
Autores principales: Zheng, Min, Karki, Rajendra, Kancharana, Balabhaskararao, Berns, Hartmut, Pruett-Miller, Shondra M., Kanneganti, Thirumala-Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633687/
https://www.ncbi.nlm.nih.gov/pubmed/34740613
http://dx.doi.org/10.1016/j.jbc.2021.101379

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