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Single-cell measurements of two-dimensional binding affinity across cell contacts

The two-dimensional (2D) affinity between protein molecules across contacting cells is a key parameter regulating and initiating several cellular processes. However, measuring 2D affinity can be challenging, and experimental data are limited. In addition, the obtained 2D affinities are typically ave...

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Detalles Bibliográficos
Autores principales: Chouliara, Manto, Junghans, Victoria, Dam, Tommy, Santos, Ana Mafalda, Davis, Simon J., Jönsson, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633712/
https://www.ncbi.nlm.nih.gov/pubmed/34653390
http://dx.doi.org/10.1016/j.bpj.2021.10.010