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Modulation of the blood-tumor barrier to enhance drug delivery and efficacy for brain metastases
The blood-brain barrier is the selectively permeable vasculature of the brain vital for maintaining homeostasis and neurological function. Low permeability is beneficial in the presence of toxins and pathogens in the blood. However, in the presence of metastatic brain tumors, it is a challenge for d...
Autores principales: | Blethen, Kathryn E, Arsiwala, Tasneem A, Fladeland, Ross A, Sprowls, Samuel A, Panchal, Dhruvi M, Adkins, Chris E, Kielkowski, Brooke N, Earp, Leland E, Glass, Morgan J, Pritt, Trenton A, Cabuyao, Yssabela M, Aulakh, Sonikpreet, Lockman, Paul R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633736/ https://www.ncbi.nlm.nih.gov/pubmed/34859240 http://dx.doi.org/10.1093/noajnl/vdab123 |
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