MYC regulates metabolism through vesicular transfer of glycolytic kinases

Amplification of the proto-oncogene MYCN is a key molecular aberration in high-risk neuroblastoma and predictive of poor outcome in this childhood malignancy. We investigated the role of MYCN in regulating the protein cargo of extracellular vesicles (EVs) secreted by tumour cells that can be interna...

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Detalles Bibliográficos
Autores principales: Tsakaneli, Alexia, Carregari, Victor Corasolla, Morini, Martina, Eva, Alessandra, Cangemi, Giuliana, Chayka, Olesya, Makarov, Evgeny, Bibbò, Sandra, Capone, Emily, Sala, Gianluca, De Laurenzi, Vincenzo, Poon, Evon, Chesler, Louis, Pieroni, Luisa, Larsen, Martin R., Palmisano, Giuseppe, Sala, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633805/
https://www.ncbi.nlm.nih.gov/pubmed/34847775
http://dx.doi.org/10.1098/rsob.210276

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