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Lymph node swelling combined with temporary effector T cell retention aids T cell response in a model of adaptive immunity

Swelling of lymph nodes (LNs) is commonly observed during the adaptive immune response, yet the impact on T cell (TC) trafficking and subsequent immune response is not well known. To better understand the effect of macro-scale alterations, we developed an agent-based model of the LN paracortex, desc...

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Detalles Bibliográficos
Autores principales: Johnson, Sarah C., Frattolin, Jennifer, Edgar, Lowell T., Jafarnejad, Mohammad, Moore Jr, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633806/
https://www.ncbi.nlm.nih.gov/pubmed/34847790
http://dx.doi.org/10.1098/rsif.2021.0464