Cargando…

Impairment of Multiple Mitochondrial Energy Metabolism Pathways in the Heart of Chagas Disease Cardiomyopathy Patients

Chagas disease cardiomyopathy (CCC) is an inflammatory dilated cardiomyopathy occurring in 30% of the 6 million infected with the protozoan Trypanosoma cruzi in Latin America. Survival is significantly lower in CCC than ischemic (IC) and idiopathic dilated cardiomyopathy (DCM). Previous studies disc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Teixeira, Priscila Camillo, Ducret, Axel, Langen, Hanno, Nogoceke, Everson, Santos, Ronaldo Honorato Barros, Silva Nunes, João Paulo, Benvenuti, Luiz, Levy, Debora, Bydlowski, Sergio Paulo, Bocchi, Edimar Alcides, Kuramoto Takara, Andréia, Fiorelli, Alfredo Inácio, Stolf, Noedir Antonio, Pomeranzeff, Pablo, Chevillard, Christophe, Kalil, Jorge, Cunha-Neto, Edecio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633876/ https://www.ncbi.nlm.nih.gov/pubmed/34867990 http://dx.doi.org/10.3389/fimmu.2021.755782

Ejemplares similares

Myocardial Gene Expression of T-bet, GATA-3, Ror-γt, FoxP3, and Hallmark Cytokines in Chronic Chagas Disease Cardiomyopathy: An Essentially Unopposed T(H)1-Type Response
por: Nogueira, Luciana Gabriel, et al.
Publicado: (2014)

Selective Decrease of Components of the Creatine Kinase System and ATP Synthase Complex in Chronic Chagas Disease Cardiomyopathy
por: Teixeira, Priscila Camillo, et al.
Publicado: (2011)

Myocardial Chemokine Expression and Intensity of Myocarditis in Chagas Cardiomyopathy Are Controlled by Polymorphisms in CXCL9 and CXCL10
por: Nogueira, Luciana Gabriel, et al.
Publicado: (2012)

Chagas’ disease: the hidden enemy around the world
por: Bocchi, Edimar Alcides
Publicado: (2022)

Co-Exposure of Cardiomyocytes to IFN-γ and TNF-α Induces Mitochondrial Dysfunction and Nitro-Oxidative Stress: Implications for the Pathogenesis of Chronic Chagas Disease Cardiomyopathy
por: Nunes, João Paulo Silva, et al.
Publicado: (2021)

miRNAs may play a major role in the control of gene expression in key pathobiological processes in Chagas disease cardiomyopathy
por: Laugier, Laurie, et al.
Publicado: (2020)

Whole-Genome Cardiac DNA Methylation Fingerprint and Gene Expression Analysis Provide New Insights in the Pathogenesis of Chronic Chagas Disease Cardiomyopathy
por: Laugier, Laurie, et al.
Publicado: (2017)

Polymorphism in the Alpha Cardiac Muscle Actin 1 Gene Is Associated to Susceptibility to Chronic Inflammatory Cardiomyopathy
por: Frade, Amanda Farage, et al.
Publicado: (2013)

Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy
por: Brochet, Pauline, et al.
Publicado: (2022)

Reply: Sacubitril/valsartan for Chagas' heart disease heart failure?
por: Bocchi, Edimar Alcides, et al.
Publicado: (2018)

Chagas Disease Megaesophagus Patients Carrying Variant MRPS18B P260A Display Nitro-Oxidative Stress and Mitochondrial Dysfunction in Response to IFN-γ Stimulus
por: Silva, Karla Deysiree Alcântara, et al.
Publicado: (2022)

Matrix Metalloproteinase 2 and 9 Enzymatic Activities are Selectively Increased in the Myocardium of Chronic Chagas Disease Cardiomyopathy Patients: Role of TIMPs
por: Baron, Monique Andrade, et al.
Publicado: (2022)

Chagas Disease Cardiomyopathy: Immunopathology and Genetics
por: Cunha-Neto, Edecio, et al.
Publicado: (2014)

The course of patients with Chagas heart disease during episodes of decompensated heart failure
por: Issa, Victor Sarli, et al.
Publicado: (2021)

NHETS − Necropsy Heart Transplantation Study
por: Valette, Thiago Ninck, et al.
Publicado: (2014)

Safety profile and efficacy of ivabradine in heart failure due to Chagas heart disease: a post hoc analysis of the SHIFT trial
por: Bocchi, Edimar Alcides, et al.
Publicado: (2017)

Disease Tolerance and Pathogen Resistance Genes May Underlie Trypanosoma cruzi Persistence and Differential Progression to Chagas Disease Cardiomyopathy
por: Chevillard, Christophe, et al.
Publicado: (2018)

Heart Failure in South America
por: Bocchi, Edimar Alcides
Publicado: (2013)

Three and two-dimensional cardiac mechanics by speckle tracking are predictors of outcomes in chagas heart disease
por: Hotta, Viviane Tiemi, et al.
Publicado: (2022)

Management of Cardiovascular Disease in Patients With COVID-19 and Chronic Chagas Disease: Implications to Prevent a Scourge Still Larger
por: Bestetti, Reinaldo Bulgarelli, et al.
Publicado: (2022)

Catheter Ablation for Atrial Fibrillation in Patients with Heart Failure
por: Scanavacca, Mauricio, et al.
Publicado: (2018)

Comment on “MicroRNA-208a Silencing Attenuates Doxorubicin Induced Myocyte Apoptosis and Cardiac Dysfunction”
por: Oliveira-Carvalho, Vagner, et al.
Publicado: (2016)

Quality of Life in Heart Failure: An Important Goal in Treatment
por: Gomes, Brenno Rizerio, et al.
Publicado: (2020)

Bloqueio do Ramo Esquerdo Idiopático e Sintomas Inexplicáveis Durante o Exercício: Um Relato de Caso
por: Guimarães, Guilherme Veiga, et al.
Publicado: (2020)

Clinical findings and prognosis of patients hospitalized for acute decompensated heart failure: Analysis of the influence of Chagas etiology and ventricular function
por: Terhoch, Caíque Bueno, et al.
Publicado: (2018)

Effects of Oxysterols on Immune Cells and Related Diseases
por: de Freitas, Fábio Alessandro, et al.
Publicado: (2022)

Current strategies for preventing renal dysfunction in patients with heart failure: a heart failure stage approach
por: Issa, Victor Sarli, et al.
Publicado: (2013)

History of Heart Transplantation: a Hard and Glorious Journey
por: Stolf, Noedir A. G.
Publicado: (2017)

Comment on "Heart Injury with Projectile Lodged Inside the Heart"
por: Stolf, Noedir Antônio Groppo
Publicado: (2019)

Xenotransplantation: on the way to Clinical Application?
por: Stolf, Noedir Antônio Groppo
Publicado: (2019)

Reproducibility of the Self-Controlled Six-Minute Walking Test in Heart Failure Patients
por: Guimarães, Guilherme Veiga, et al.
Publicado: (2008)

The Relationship Between Heart Rate Reserve and Oxygen Uptake Reserve in Heart Failure Patients on Optimized and Non-Optimized Beta-Blocker Therapy
por: Carvalho, Vitor Oliveira, et al.
Publicado: (2008)

Endothelial function in pre-pubertal children at risk of developing cardiomyopathy: a new frontier
por: Tavares, Aline Cristina, et al.
Publicado: (2012)

Hydrotherapy in Heart Failure: A Case Report
por: Carvalho, Vitor Oliveira, et al.
Publicado: (2009)

Functional Class in Children with Idiopathic Dilated Cardiomyopathy. A pilot Study
por: Tavares, Aline Cristina, et al.
Publicado: (2016)

Aging, cardiotoxicity, and chemotherapy
por: Bocchi, Edimar Alcides, et al.
Publicado: (2019)

Long-term Results of a Cardiology Postgraduate Program
por: Bocchi, Edimar Alcides, et al.
Publicado: (2017)

Mode of Death on Chagas Heart Disease: Comparison with Other Etiologies. A Subanalysis of the REMADHE Prospective Trial
por: Ayub-Ferreira, Silvia M., et al.
Publicado: (2013)

ChagasDB: 80 years of publicly available data on the molecular host response to Trypanosoma cruzi infection in a single database
por: Brochet, Pauline, et al.
Publicado: (2023)

Mitochondria as a Cellular Hub in Infection and Inflammation
por: Andrieux, Pauline, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7jnfhddod8ojnuend93ns7rsv3