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STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia
Inflammatory responses are crucial for regeneration following peripheral nerve injury (PNI). PNI triggers inflammatory responses at the site of injury. The DNA-sensing receptor cyclic GMP-AMP synthase (cGAS) and its downstream effector stimulator of interferon genes (STING) sense foreign and self-DN...
Autores principales: | Morozzi, Giulio, Rothen, Julian, Toussaint, Gauthier, De Lange, Katrina, Westritschnig, Katrin, Doelemeyer, Arno, Ueberschlag, Vanessa Pitiot, Kahle, Peter, Lambert, Christian, Obrecht, Michael, Beckmann, Nicolau, Ritter, Veronique, Panesar, Moh, Stauffer, Daniela, Garnier, Isabelle, Mueller, Matthias, Guerini, Danilo, Keller, Caroline Gubser, Knehr, Judith, Roma, Guglielmo, Bidinosti, Michael, Brachat, Sophie, Morvan, Frederic, Fornaro, Mara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633968/ https://www.ncbi.nlm.nih.gov/pubmed/34877494 http://dx.doi.org/10.1016/j.isci.2021.103434 |
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