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Inhibition of extracellular vesicle-associated MMP2 abrogates intercellular hepatic miR-122 transfer to liver macrophages and curtails inflammation

Hepatic miRNA, miR-122, plays an important role in controlling metabolic homeostasis in mammalian liver. Intercellular transfer of miR-122 was found to play a role in controlling tissue inflammation. miR-122, as part of extracellular vesicles released by lipid-exposed hepatic cells, are taken up by...

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Detalles Bibliográficos
Autores principales:	Das, Arnab, Basu, Sudarshana, Bandyopadhyay, Diptankar, Mukherjee, Kamalika, Datta, Debduti, Chakraborty, Sreemoyee, Jana, Sayantan, Adak, Moumita, Bose, Sarpita, Chakrabarti, Saikat, Swarnakar, Snehasikta, Chakrabarti, Partha, Bhattacharyya, Suvendra N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633982/ https://www.ncbi.nlm.nih.gov/pubmed/34877493 http://dx.doi.org/10.1016/j.isci.2021.103428

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