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Pharmacological targeting of Sam68 functions in colorectal cancer stem cells

Cancer stem cells (CSCs) are documented to play a key role in tumorigenesis and therapy resistance. Despite significant progress in clinical oncology, CSC reservoirs remain elusive and difficult to eliminate. Reverse-turn peptidomimetics were characterized as disruptors of CBP/beta-Catenin interacti...

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Detalles Bibliográficos
Autores principales: Masibag, Angelique N., Bergin, Christopher J., Haebe, Joshua R., Zouggar, Aïcha, Shah, Muhammad S., Sandouka, Tamara, Mendes da Silva, Amanda, Desrochers, François M., Fournier-Morin, Aube, Benoit, Yannick D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633986/
https://www.ncbi.nlm.nih.gov/pubmed/34877499
http://dx.doi.org/10.1016/j.isci.2021.103442