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The spatiotemporal changes in dopamine, neuromelanin and iron characterizing Parkinson’s disease
In Parkinson’s disease, there is a progressive reduction in striatal dopaminergic function, and loss of neuromelanin-containing dopaminergic neurons and increased iron deposition in the substantia nigra. We tested the hypothesis of a relationship between impairment of the dopaminergic system and cha...
Autores principales: | Biondetti, Emma, Santin, Mathieu D, Valabrègue, Romain, Mangone, Graziella, Gaurav, Rahul, Pyatigorskaya, Nadya, Hutchison, Matthew, Yahia-Cherif, Lydia, Villain, Nicolas, Habert, Marie-Odile, Arnulf, Isabelle, Leu-Semenescu, Smaranda, Dodet, Pauline, Vila, Miquel, Corvol, Jean-Christophe, Vidailhet, Marie, Lehéricy, Stéphane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634084/ https://www.ncbi.nlm.nih.gov/pubmed/33978742 http://dx.doi.org/10.1093/brain/awab191 |
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