The Hda1 histone deacetylase limits divergent non‐coding transcription and restricts transcription initiation frequency

Nucleosome‐depleted regions (NDRs) at gene promoters support initiation of RNA polymerase II transcription. Interestingly, transcription often initiates in both directions, resulting in an mRNA and a divergent non‐coding (DNC) transcript of unclear purpose. Here, we characterized the genetic archite...

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Detalles Bibliográficos
Autores principales: Gowthaman, Uthra, Ivanov, Maxim, Schwarz, Isabel, Patel, Heta P, Müller, Niels A, García‐Pichardo, Desiré, Lenstra, Tineke L, Marquardt, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634119/
https://www.ncbi.nlm.nih.gov/pubmed/34661296
http://dx.doi.org/10.15252/embj.2021108903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634119/
https://www.ncbi.nlm.nih.gov/pubmed/34661296
http://dx.doi.org/10.15252/embj.2021108903

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