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The Hda1 histone deacetylase limits divergent non‐coding transcription and restricts transcription initiation frequency
Nucleosome‐depleted regions (NDRs) at gene promoters support initiation of RNA polymerase II transcription. Interestingly, transcription often initiates in both directions, resulting in an mRNA and a divergent non‐coding (DNC) transcript of unclear purpose. Here, we characterized the genetic archite...
Autores principales: | Gowthaman, Uthra, Ivanov, Maxim, Schwarz, Isabel, Patel, Heta P, Müller, Niels A, García‐Pichardo, Desiré, Lenstra, Tineke L, Marquardt, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634119/ https://www.ncbi.nlm.nih.gov/pubmed/34661296 http://dx.doi.org/10.15252/embj.2021108903 |
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