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Pharmacological SARM1 inhibition protects axon structure and function in paclitaxel-induced peripheral neuropathy
Axonal degeneration is an early and ongoing event that causes disability and disease progression in many neurodegenerative disorders of the peripheral and central nervous systems. Chemotherapy-induced peripheral neuropathy (CIPN) is a major cause of morbidity and the main cause of dose reductions an...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634121/ https://www.ncbi.nlm.nih.gov/pubmed/33964142 http://dx.doi.org/10.1093/brain/awab184 |