PBX1 Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence and Apoptosis by Alleviating Reactive Oxygen Species-Mediated DNA Damage Instead of Enhancing DNA Damage Repair

Tissues and organs undergo structural deterioration and functional decline during aging. DNA damage is considered a major cause of stem cell senescence. Although stem cells develop sophisticated DNA repair systems, when the intrinsic and extrinsic insults exceed the DNA repair capacity, cellular sen...

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Detalles Bibliográficos
Autores principales: Wang, Yuan, Sui, Yutong, Lian, Aobo, Han, Xing, Liu, Feilin, Zuo, Kuiyang, Liu, Mingsheng, Sun, Wei, Wang, Ziyu, Liu, Zinan, Zou, Fei, Lu, Rifeng, Jin, Minghua, Du, Haiying, Xu, Kan, Liu, Xiaomei, Liu, Jinyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634257/
https://www.ncbi.nlm.nih.gov/pubmed/34869323
http://dx.doi.org/10.3389/fcell.2021.739868

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