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Intramuscular Vaccination With the HSV-1(VC2) Live-Attenuated Vaccine Strain Confers Protection Against Viral Ocular Immunopathogenesis Associated With γδT Cell Intracorneal Infiltration
Herpes simplex virus type-1 (HSV-1) ocular infection is one of the leading causes of infectious blindness in developed countries. The resultant herpetic keratitis (HK) is caused by an exacerbated reaction of the adaptive immune response that persists beyond virus clearance causing substantial damage...
Autores principales: | Nabi, Rafiq, Lewin, Andrew C., Collantes, Therese M., Chouljenko, Vladimir N., Kousoulas, Konstantin G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634438/ https://www.ncbi.nlm.nih.gov/pubmed/34868077 http://dx.doi.org/10.3389/fimmu.2021.789454 |
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