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Rivaroxaban Suppresses Atherosclerosis by Inhibiting FXa-Induced Macrophage M1 Polarization-Mediated Phenotypic Conversion of Vascular Smooth Muscle Cells

Background: Factor Xa (FXa) is a mediator initiating and accelerating atherosclerosis (AS). Both macrophage and vascular smooth muscle cells (VSMCs) participate in AS progression. This study was aimed to investigate the mechanisms underlying the effects of the FXa inhibitor rivaroxaban on AS. Method...

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Detalles Bibliográficos
Autores principales:	Ma, Yanpeng, Zhang, Yong, Qiu, Chuan, He, Chunhui, He, Ting, Shi, Shuang, Liu, Zhongwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634446/ https://www.ncbi.nlm.nih.gov/pubmed/34869643 http://dx.doi.org/10.3389/fcvm.2021.739212

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