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Discovery of 9,10-dihydrophenanthrene derivatives as SARS-CoV-2 3CL(pro) inhibitors for treating COVID-19
The epidemic coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has now spread worldwide and efficacious therapeutics are urgently needed. 3-Chymotrypsin-like cysteine protease (3CL(pro)) is an indispensable protein in viral replication and rep...
Autores principales: | Zhang, Jian-Wei, Xiong, Yuan, Wang, Feng, Zhang, Fu-Mao, Yang, Xiaodi, Lin, Guo-Qiang, Tian, Ping, Ge, Guangbo, Gao, Dingding |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Masson SAS.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634693/ https://www.ncbi.nlm.nih.gov/pubmed/34883292 http://dx.doi.org/10.1016/j.ejmech.2021.114030 |
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