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Discovery of 9,10-dihydrophenanthrene derivatives as SARS-CoV-2 3CL(pro) inhibitors for treating COVID-19

The epidemic coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has now spread worldwide and efficacious therapeutics are urgently needed. 3-Chymotrypsin-like cysteine protease (3CL(pro)) is an indispensable protein in viral replication and rep...

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Detalles Bibliográficos
Autores principales: Zhang, Jian-Wei, Xiong, Yuan, Wang, Feng, Zhang, Fu-Mao, Yang, Xiaodi, Lin, Guo-Qiang, Tian, Ping, Ge, Guangbo, Gao, Dingding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634693/
https://www.ncbi.nlm.nih.gov/pubmed/34883292
http://dx.doi.org/10.1016/j.ejmech.2021.114030

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