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From Microbiome to Inflammation: The Key Drivers of Cervical Cancer

Cervical cancer is the third leading cause of cancer-related death worldwide. Microbes and hosts form a mutually beneficial symbiosis relationship, and various parts of the host body are microbial habitats. Microbes can trigger inflammation in certain parts of the host body, contributing to cervical...

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Detalles Bibliográficos
Autores principales: Zhou, Zi-Wei, Long, Hui-Zhi, Cheng, Yan, Luo, Hong-Yu, Wen, Dan-Dan, Gao, Li-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634716/
https://www.ncbi.nlm.nih.gov/pubmed/34867901
http://dx.doi.org/10.3389/fmicb.2021.767931
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author Zhou, Zi-Wei
Long, Hui-Zhi
Cheng, Yan
Luo, Hong-Yu
Wen, Dan-Dan
Gao, Li-Chen
author_facet Zhou, Zi-Wei
Long, Hui-Zhi
Cheng, Yan
Luo, Hong-Yu
Wen, Dan-Dan
Gao, Li-Chen
author_sort Zhou, Zi-Wei
collection PubMed
description Cervical cancer is the third leading cause of cancer-related death worldwide. Microbes and hosts form a mutually beneficial symbiosis relationship, and various parts of the host body are microbial habitats. Microbes can trigger inflammation in certain parts of the host body, contributing to cervical cancer development. This article reviews the relationship between cervicovaginal microbes, inflammation and cervical cancer, and discusses the effect of some key cervical microbes on cervical cancer. Finally, probiotic therapy and immunotherapy are summarized.
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spelling pubmed-86347162021-12-02 From Microbiome to Inflammation: The Key Drivers of Cervical Cancer Zhou, Zi-Wei Long, Hui-Zhi Cheng, Yan Luo, Hong-Yu Wen, Dan-Dan Gao, Li-Chen Front Microbiol Microbiology Cervical cancer is the third leading cause of cancer-related death worldwide. Microbes and hosts form a mutually beneficial symbiosis relationship, and various parts of the host body are microbial habitats. Microbes can trigger inflammation in certain parts of the host body, contributing to cervical cancer development. This article reviews the relationship between cervicovaginal microbes, inflammation and cervical cancer, and discusses the effect of some key cervical microbes on cervical cancer. Finally, probiotic therapy and immunotherapy are summarized. Frontiers Media S.A. 2021-11-15 /pmc/articles/PMC8634716/ /pubmed/34867901 http://dx.doi.org/10.3389/fmicb.2021.767931 Text en Copyright © 2021 Zhou, Long, Cheng, Luo, Wen and Gao. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Zhou, Zi-Wei
Long, Hui-Zhi
Cheng, Yan
Luo, Hong-Yu
Wen, Dan-Dan
Gao, Li-Chen
From Microbiome to Inflammation: The Key Drivers of Cervical Cancer
title From Microbiome to Inflammation: The Key Drivers of Cervical Cancer
title_full From Microbiome to Inflammation: The Key Drivers of Cervical Cancer
title_fullStr From Microbiome to Inflammation: The Key Drivers of Cervical Cancer
title_full_unstemmed From Microbiome to Inflammation: The Key Drivers of Cervical Cancer
title_short From Microbiome to Inflammation: The Key Drivers of Cervical Cancer
title_sort from microbiome to inflammation: the key drivers of cervical cancer
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634716/
https://www.ncbi.nlm.nih.gov/pubmed/34867901
http://dx.doi.org/10.3389/fmicb.2021.767931
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