Cargando…
Insights Into the Role of CSF1R in the Central Nervous System and Neurological Disorders
The colony-stimulating factor 1 receptor (CSF1R) is a key tyrosine kinase transmembrane receptor modulating microglial homeostasis, neurogenesis, and neuronal survival in the central nervous system (CNS). CSF1R, which can be proteolytically cleaved into a soluble ectodomain and an intracellular prot...
Autores principales: | Hu, Banglian, Duan, Shengshun, Wang, Ziwei, Li, Xin, Zhou, Yuhang, Zhang, Xian, Zhang, Yun-Wu, Xu, Huaxi, Zheng, Honghua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634759/ https://www.ncbi.nlm.nih.gov/pubmed/34867307 http://dx.doi.org/10.3389/fnagi.2021.789834 |
Ejemplares similares
-
Minocycline protects against microgliopathy in a Csf1r haplo-insufficient mouse model of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP)
por: Li, Xin, et al.
Publicado: (2023) -
Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Interacts With Colony-Stimulating Factor 1 Receptor (CSF1R) but Is Not Necessary for CSF1/CSF1R-Mediated Microglial Survival
por: Cheng, Baoying, et al.
Publicado: (2021) -
Proteolytic Shedding of Human Colony‐Stimulating Factor 1 Receptor and its implication
por: Wei, Yue, et al.
Publicado: (2021) -
Blood-Brain Barrier: More Contributor to Disruption of Central Nervous System Homeostasis Than Victim in Neurological Disorders
por: Xiao, Minjia, et al.
Publicado: (2020) -
Enteric Nervous System: The Bridge Between the Gut Microbiota and Neurological Disorders
por: Geng, Zi-Han, et al.
Publicado: (2022)