Preparation, Antibacterial Activity, and Catalytic Application of Magnetic Graphene Oxide‐Fucoidan in the Synthesis of 1,4‐Dihydropyridines and Polyhydroquinolines

Polymer‐coated magnetic nanoparticles are emerging as a useful tool for a variety of applications, including catalysis. In the present study, fucoidan‐coated magnetic graphene oxide was synthesized using a natural sulfated polysaccharide. The prepared BaFe(12)O(19)@GO@Fu (Fu=fucoidan, GO=graphene oxide) was characterized using Fourier‐transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy‐dispersive X‐ray (EDX) analysis, vibrating sample magnetometry (VSM), thermogravimetric analysis (TGA), Raman spectroscopy, and X‐ray diffraction (XRD). The catalytic proficiency of BaFe(12)O(19)@GO@Fu was investigated in the synthesis of 1,4‐dihydropyridine and polyhydroquinoline derivatives. Excellent turnover numbers (TON) and turnover frequencies (TOF) (6330 and 25320 h(−1)) testify to the high efficiency of the catalyst. Moreover, the antimicrobial activity of BaFe(12)O(19)@GO@Fu was evaluated against Escherichia coli (E. coli), and Staphylococcus aureus (S. aureus) through the Agar well diffusion method, indicating that BaFe(12)O(19)@GO@Fu has antibacterial activity against S. aureus.