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Preparation, Antibacterial Activity, and Catalytic Application of Magnetic Graphene Oxide‐Fucoidan in the Synthesis of 1,4‐Dihydropyridines and Polyhydroquinolines
Polymer‐coated magnetic nanoparticles are emerging as a useful tool for a variety of applications, including catalysis. In the present study, fucoidan‐coated magnetic graphene oxide was synthesized using a natural sulfated polysaccharide. The prepared BaFe(12)O(19)@GO@Fu (Fu=fucoidan, GO=graphene ox...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634770/ https://www.ncbi.nlm.nih.gov/pubmed/34851041 http://dx.doi.org/10.1002/open.202100221 |
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author | Nosrati, Aliakbar Amirnejat, Sara Javanshir, Shahrzad |
author_facet | Nosrati, Aliakbar Amirnejat, Sara Javanshir, Shahrzad |
author_sort | Nosrati, Aliakbar |
collection | PubMed |
description | Polymer‐coated magnetic nanoparticles are emerging as a useful tool for a variety of applications, including catalysis. In the present study, fucoidan‐coated magnetic graphene oxide was synthesized using a natural sulfated polysaccharide. The prepared BaFe(12)O(19)@GO@Fu (Fu=fucoidan, GO=graphene oxide) was characterized using Fourier‐transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy‐dispersive X‐ray (EDX) analysis, vibrating sample magnetometry (VSM), thermogravimetric analysis (TGA), Raman spectroscopy, and X‐ray diffraction (XRD). The catalytic proficiency of BaFe(12)O(19)@GO@Fu was investigated in the synthesis of 1,4‐dihydropyridine and polyhydroquinoline derivatives. Excellent turnover numbers (TON) and turnover frequencies (TOF) (6330 and 25320 h(−1)) testify to the high efficiency of the catalyst. Moreover, the antimicrobial activity of BaFe(12)O(19)@GO@Fu was evaluated against Escherichia coli (E. coli), and Staphylococcus aureus (S. aureus) through the Agar well diffusion method, indicating that BaFe(12)O(19)@GO@Fu has antibacterial activity against S. aureus. |
format | Online Article Text |
id | pubmed-8634770 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-86347702021-12-08 Preparation, Antibacterial Activity, and Catalytic Application of Magnetic Graphene Oxide‐Fucoidan in the Synthesis of 1,4‐Dihydropyridines and Polyhydroquinolines Nosrati, Aliakbar Amirnejat, Sara Javanshir, Shahrzad ChemistryOpen Full Papers Polymer‐coated magnetic nanoparticles are emerging as a useful tool for a variety of applications, including catalysis. In the present study, fucoidan‐coated magnetic graphene oxide was synthesized using a natural sulfated polysaccharide. The prepared BaFe(12)O(19)@GO@Fu (Fu=fucoidan, GO=graphene oxide) was characterized using Fourier‐transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy‐dispersive X‐ray (EDX) analysis, vibrating sample magnetometry (VSM), thermogravimetric analysis (TGA), Raman spectroscopy, and X‐ray diffraction (XRD). The catalytic proficiency of BaFe(12)O(19)@GO@Fu was investigated in the synthesis of 1,4‐dihydropyridine and polyhydroquinoline derivatives. Excellent turnover numbers (TON) and turnover frequencies (TOF) (6330 and 25320 h(−1)) testify to the high efficiency of the catalyst. Moreover, the antimicrobial activity of BaFe(12)O(19)@GO@Fu was evaluated against Escherichia coli (E. coli), and Staphylococcus aureus (S. aureus) through the Agar well diffusion method, indicating that BaFe(12)O(19)@GO@Fu has antibacterial activity against S. aureus. John Wiley and Sons Inc. 2021-12-01 /pmc/articles/PMC8634770/ /pubmed/34851041 http://dx.doi.org/10.1002/open.202100221 Text en © 2021 The Authors. Published by Wiley-VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Full Papers Nosrati, Aliakbar Amirnejat, Sara Javanshir, Shahrzad Preparation, Antibacterial Activity, and Catalytic Application of Magnetic Graphene Oxide‐Fucoidan in the Synthesis of 1,4‐Dihydropyridines and Polyhydroquinolines |
title | Preparation, Antibacterial Activity, and Catalytic Application of Magnetic Graphene Oxide‐Fucoidan in the Synthesis of 1,4‐Dihydropyridines and Polyhydroquinolines |
title_full | Preparation, Antibacterial Activity, and Catalytic Application of Magnetic Graphene Oxide‐Fucoidan in the Synthesis of 1,4‐Dihydropyridines and Polyhydroquinolines |
title_fullStr | Preparation, Antibacterial Activity, and Catalytic Application of Magnetic Graphene Oxide‐Fucoidan in the Synthesis of 1,4‐Dihydropyridines and Polyhydroquinolines |
title_full_unstemmed | Preparation, Antibacterial Activity, and Catalytic Application of Magnetic Graphene Oxide‐Fucoidan in the Synthesis of 1,4‐Dihydropyridines and Polyhydroquinolines |
title_short | Preparation, Antibacterial Activity, and Catalytic Application of Magnetic Graphene Oxide‐Fucoidan in the Synthesis of 1,4‐Dihydropyridines and Polyhydroquinolines |
title_sort | preparation, antibacterial activity, and catalytic application of magnetic graphene oxide‐fucoidan in the synthesis of 1,4‐dihydropyridines and polyhydroquinolines |
topic | Full Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634770/ https://www.ncbi.nlm.nih.gov/pubmed/34851041 http://dx.doi.org/10.1002/open.202100221 |
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