Deletion of Oncomodulin Gives Rise to Early Progressive Cochlear Dysfunction in C57 and CBA Mice

Ca(2+) signaling is a major contributor to sensory hair cell function in the cochlea. Oncomodulin (OCM) is a Ca(2+) binding protein (CaBP) preferentially expressed in outer hair cells (OHCs) of the cochlea and few other specialized cell types. Here, we expand on our previous reports and show that OC...

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Detalles Bibliográficos
Autores principales: Climer, Leslie K., Hornak, Aubrey J., Murtha, Kaitlin, Yang, Yang, Cox, Andrew M., Simpson, Preston L., Le, Andy, Simmons, Dwayne D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634891/
https://www.ncbi.nlm.nih.gov/pubmed/34867279
http://dx.doi.org/10.3389/fnagi.2021.749729

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