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An ECHO of Cartilage: In Silico Prediction of Combinatorial Treatments to Switch Between Transient and Permanent Cartilage Phenotypes With Ex Vivo Validation
A fundamental question in cartilage biology is: what determines the switch between permanent cartilage found in the articular joints and transient hypertrophic cartilage that functions as a template for bone? This switch is observed both in a subset of OA patients that develop osteophytes, as well a...
Autores principales: | Khurana, Sakshi, Schivo, Stefano, Plass, Jacqueline R. M., Mersinis, Nikolas, Scholma, Jetse, Kerkhofs, Johan, Zhong, Leilei, van de Pol, Jaco, Langerak, Rom, Geris, Liesbet, Karperien, Marcel, Post, Janine N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634894/ https://www.ncbi.nlm.nih.gov/pubmed/34869253 http://dx.doi.org/10.3389/fbioe.2021.732917 |
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