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An ECHO of Cartilage: In Silico Prediction of Combinatorial Treatments to Switch Between Transient and Permanent Cartilage Phenotypes With Ex Vivo Validation

A fundamental question in cartilage biology is: what determines the switch between permanent cartilage found in the articular joints and transient hypertrophic cartilage that functions as a template for bone? This switch is observed both in a subset of OA patients that develop osteophytes, as well a...

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Detalles Bibliográficos
Autores principales: Khurana, Sakshi, Schivo, Stefano, Plass, Jacqueline R. M., Mersinis, Nikolas, Scholma, Jetse, Kerkhofs, Johan, Zhong, Leilei, van de Pol, Jaco, Langerak, Rom, Geris, Liesbet, Karperien, Marcel, Post, Janine N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634894/
https://www.ncbi.nlm.nih.gov/pubmed/34869253
http://dx.doi.org/10.3389/fbioe.2021.732917

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