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Combined Deficiency of the Melanocortin 5 Receptor and Adenosine 2A Receptor Unexpectedly Provides Resistance to Autoimmune Disease in a CD8(+) T Cell-Dependent Manner

Regulatory immunity that provides resistance to relapse emerges during resolution of experimental autoimmune uveitis (EAU). This post-EAU regulatory immunity requires a melanocortin 5 receptor (MC5r)-dependent suppressor antigen presenting cell (APC), as shown using a MC5r single knock-out mouse. Th...

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Detalles Bibliográficos
Autores principales:	McDonald, Trisha, Muhammad, Fauziyya, Peters, Kayleigh, Lee, Darren J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634946/ https://www.ncbi.nlm.nih.gov/pubmed/34867964 http://dx.doi.org/10.3389/fimmu.2021.742154

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