Cargando…

The NF-κB Transcription Factor c-Rel Modulates Group 2 Innate Lymphoid Cell Effector Functions and Drives Allergic Airway Inflammation

Group 2 innate lymphoid cells (ILC2s) play a key role in the initiation and orchestration of early type 2 immune responses. Upon tissue damage, ILC2s are activated by alarmins such as IL-33 and rapidly secrete large amounts of type 2 signature cytokines. ILC2 activation is governed by a network of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Mindt, Barbara C., Krisna, Sai Sakktee, Duerr, Claudia U., Mancini, Mathieu, Richer, Lara, Vidal, Silvia M., Gerondakis, Steven, Langlais, David, Fritz, Jörg H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635195/
https://www.ncbi.nlm.nih.gov/pubmed/34867937
http://dx.doi.org/10.3389/fimmu.2021.664218